Plasma-activated medium induced apoptosis on glioblastoma brain tumor cells by inhibiting growth/survival signaling
نویسندگان
چکیده
Glioblastoma brain tumor cells and normal cells were treated with plasma-activated medium (PAM). Cell proliferation assays showed that glioblastoma cells were selectively killed by PAM. PAM induced apoptosis on glioblastoma. There are many signaling pathways that lead to apoptosis. We found that PAM downregulated the PI3K/PTEN-AKT pathway that is responsible for cell survival and proliferation on glioblastoma.
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